IMPORTANT-CaseStudyEXAM
Biomedical Sciences exam
ClinicalImmunology and Immunohaematology
6BIOM003W
Case History Exam Section A July 2021
Patient HB is a non-sensitised, 45 year old male, who was diagnosed with kidney
failure caused by IgA nephropathy. 30 months ago, he received a renal transplant
from his wife, DB.
Initially the kidney functioned well, however over the last 6 months function has been
deteriorating and there are signs of rejection.
Blood group HLA-A HLA-B HLA-Cw HLA- DR HLA-DQ
Patient HB
(recipient)
O RhD
+ve A*29, A*02 B*44, B*7
Cw*16,
Cw*07
DRB1*11
DRB1*15
DQB1*0301
DQB1*06
Wife DB
(Donor)
O RhD
+ve A*03, A*02 B*27, B*44
Cw*02,
Cw*05
DRB1*11
DRB1*04
DQB1*0301
DQB1*0302
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