both assignments down below
Journal 2: Notice and Focus
STEP 1: Find a passage about 10-12 sentences (if poetry, think more in terms of lines) long that you do not fully understand but also grabs your attention. Carefully read and reread this selection before getting started.
Type the passage here
STEP 2: Ask yourself, “What do I notice?”
Write down a list of at least five specific words, phrases, or other textual details that you notice from the passage that seem interesting, surprising, or strange. By textual features, I mean just about anything you see–including grammar, punctuation, and more typical literary features like metaphor, symbol, character, setting, etc. Be specific as you note these.
You do not have to explain or fully understand these features. An easy way for you do this is to use “interesting,” “revealing,” or “surprising” as guides to your reaction. (I found this moment strange–it’s easy to take a note with “Strange” in the margin)
Answer here.
STEP 3: Ask yourself, “What do I find strange or confusing?”
Write down a list of at least three moments from the passage that you notice. What makes each strange/confusing and why?
Answer here.
STEP 4: Rank, in order, the features from steps 2 and 3 that from most interesting to least interesting.
Answer here.
Step 5: Pick the top three items in your list for you to work on in your journal. As you start to write, ask yourself, “Why is this interesting?” and “So what?” as you write. Start with one and write as much as you can, then on another until you have 600 words. I want to see you think through the specific features you found above. You can make connections to other parts of the text you read, but really focus in on the details in this specific passage as you work.
Answer here.
Question 1.1. What is the 1000 genomes project?
Question 1.2. What are the super populations and sub-populations that contributed genomic DNA to the 1000 genomes project?
Question 1.3. Why are the ACE2 and TMPRSS2 human genes of interest when it comes to understanding the severity of covid infection?
Question 2.1. Make labelled figures for, or describe (or do both) the headers of a typical FASTQ, SAM/BAM and VCF file, include column heading descriptions where appropriate – highlight what they have in common and what is unique to each file type. The goal here is to be able to recognize when you have successfully created / downloaded a VCF file and understand what it looks like so that we can import it into Rstudio
Question 3.1: what does ACE stand for?
Question 3.2. On which chromosome do we find the human ACE2 gene?
Question 3.3. How many different orthologous genes of ACE2 have been sequenced and name at least 1 vertebrate and 1 invertebrate in which it is found.
Question 4.1: what does BASH stand for?
Question 4.2: What is a directory? Do directories have extensions like .exe or .txt?
Question 4.3: using some of the commands you are learning about, briefly describe what the man command does (make sure you understand what the command q does beforehand)